The primary purpose of this study is to help answer if LY2127399 is safe and effective in the treatment of rheumatoid arthritis while on a background treatment of methotrexate.

This study is comprised of 3 periods:

Period 1 - 52 week blinded treatment

Period 2 - additional 48 week unblinded treatment

Period 3 - 48 week post treatment follow up

Read more: http://www.clinicaltrials.gov/ct2/show/NCT01198002?cond=%22Arthritis%22&lup_s=07/14/2011&lup_d=30