Given every 4 weeks for 24 weeks. Patients receive a 240mg loading dose when initiating treatment.

During the Treatment Period, for blinding purposes, patients will alternate injections of LY2127399 and injections of placebo every 2 weeks.

After 16 weeks, non-responders will receive 90 mg every 2 weeks.

Read more: http://www.clinicaltrials.gov/ct2/show/NCT01202773?cond=%22Arthritis%22&lup_s=07/28/2011&lup_d=30