Following specific pharmacokinetics parameters will be used:
C max - maximal concentration, AUC(0-t) - area under the curve concentration-time until the last time point of concentration measurement, AUC(0-∞) - area under the curve concentration-time extrapolated to infinity, T1/2 - final elimination half-life, Lambda z - elimination rate constant, CL - clearance, Vss - volume of distribution in steady state, C trough - trough concentration after multiple administration.
Read more: http://www.clinicaltrials.gov/ct2/show/NCT01990157?cond=%22Arthritis%22&lup_s=10/31/2013&lup_d=30
