ECL=Electrochemiluminescence

For the ECL assay, for all summaries and listings unless specified otherwise, a positive immunogenicity response for 'CTLA4 and possibly Ig', 'Ig and/or Junction Region', respectively, is defined as:

  • A missing baseline immunogenicity measurement and a positive analytical laboratory reported immunogenicity response post-baseline
  • A negative baseline immunogenicity response and a positive analytical laboratory reported immunogenicity response post-baseline
  • A positive baseline immunogenicity response and a positive analytical laboratory reported immunogenicity response post-baseline that has a titer value strictly greater than the baseline titer value

Read more: http://www.clinicaltrials.gov/ct2/show/NCT01890473?cond=%22Arthritis%22&lup_s=10/31/2013&lup_d=30