Scientist /Engineer - Steadman Philippon Research Institute

This job positing is for a Scientist / Engineer in the Program for Bone Repair and Regenerative Therapeutics led by Dr. Chelsea Bahney. The long-term research goal of our group is to develop translationally relevant therapies or diagnostics that improve musculoskeletal health. The group’s research focuses largely on the central process of endochondral ossification, which is the mechanism of indirect bone formation by which cartilage transforms into bone during embryonic development, postnatal growth, fracture healing, and osteoarthritis.

INSTITUTE OVERVIEW:

The Steadman Philippon Research Institute’s (SPRIs) Mission is unlocking the secrets of healing, finding cures, and enhancing lives through global leadership in regenerative medicine, scientific research, innovation, and education. SPRI is comprised of several distinct departments that are committed to enhancing patient lives and keeping people active. Scientists, researchers, and technicians not only conduct science within their departments but also in collaborative, cross-disciplinary projects across the institute and with physicians at The Steadman Clinic. The result is a multifaceted research organization committed to team science. Scientists and researchers are underway on numerous projects, including clinical trials funded by the National Institutes of Health (NIH), Department of Defense (DoD) and industry, alongside federally funded preclinical projects and pilot programs sponsored by philanthropy. The Center for Regenerative Medicine is led by Johnny Huard, PhD, who serves as Chief Scientific Officer of SPRI.

The Center for Regenerative and Personalized Medicine (CRPM) is one department at SPRI and includes several programs that investigate cellular science and regenerative medicine techniques and therapies. Each program is led by a Principal Investigator.

CRPM PROGRAMS:

• Bone Repair and Regenerative Therapeutics
• Muscle Repair and Stem Cell Biology
• Bone and Cartilage Repair and Stem Cell Biology 
• Genetic and Cellular Engineering
• Stem Cell Engineering and Cartilage Regeneration 
• Healthy Aging and Diagnostics

The Scientist / Engineer position is designed for an PhD level scientist with advanced knowledge in regenerative medicine or orthopaedic surgery. This is predominantly a laboratory/bench position working on a portfolio of projects that are highly intellectual and utilizing cutting edge scientific techniques. This candidate will be capable managing multiple scientific projects independently, generating high quality data for 1st author scientific publications, and have experience preparing research proposals for funding. This person will be expected to help train/mentor junior staff in standard experimental techniques and help with troubleshooting. 

This job positing is for a Scientist / Engineer in the Program for Bone Repair and Regenerative Therapeutics led by Dr. Chelsea Bahney. The long-term research goal of our group is to develop translationally relevant therapies or diagnostics that improve musculoskeletal health. The group’s research focuses largely on the central process of endochondral ossification, which is the mechanism of indirect bone formation by which cartilage transforms into bone during embryonic development, postnatal growth, fracture healing, and osteoarthritis. By studying the molecular and cellular mechanisms of endochondral ossification, the laboratory aims to develop novel therapeutic strategies that can promote fracture repair or inhibit osteoarthritis. By utilizing interdisciplinary techniques that capitalize on engineering and developmental biology the laboratory aims to solve problems that will have a direct and significant impact on human health.

Technical

• PhD or MD in a relevant science with expertise related to Regenerative Medicine (bioengineering, stem cell biology, developmental biology, medicine, tissue engineering)
• Strong publication record.
• Technical experience with, and interest developing skills that manage complex data sets related to techniques such as: biomaterial platform evaluation, RNA sequencing, flow cytometry, biomarkers etc.  
• Excellent critical thinking skills.
• Strong organizational and data management skills.
• Ability to produce complex documents, perform analysis and maintain databases. 
• Prior experience reviewing, analyzing, and summarizing scientific literature.
• Experience working in preclinical models and developing/managing IACUC protocols. Willingness to travel to conduct animal experiments and proficiency in surgical techniques related to musculoskeletal research.