Musculoskeletal tumors are a diverse group of neoplasms that arise from various tissues of the musculoskeletal system, including bone, cartilage, muscle, and connective tissue. These tumors can be benign or malignant and can present in any age group. The World Health Organization classifies musculoskeletal tumors (Table 1) as chondrogenic (cartilage forming), osteogenic (bone forming), fibrogenic, vascular, those derived from the notochord (an embryonic spinal structure), those with many osteoclastic cells, and hematopoietic neoplasms of bone. In addition, there is the large and important category of “other mesenchymal tumors of bone”, which includes more commonly seen conditions such as simple bone...