The World Health Organization (WHO) has released a set of guidelines on the prevention of surgical site infection (SSI). The guidelines include 29 recommendations based on 26 reviews of recent evidence. 

Among other things, the guidelines recommend that:

  1. Surgical antibiotic prophylaxis be applied before and during surgery only.
  2. Orthopaedic surgery patients with known nasal colonization of Staphylococcus aureus should receive perioperative intranasal applications of mupirocin 2% ointment with or without a combination of chlorhexidine gluconate body wash.
  3. Surgical patients not be shaved (with hair removal, if necessary, performed by clipper only).
    Patients bathe or shower prior to surgery with either plain or antimicrobial soap.

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