Women at the highest genetic risk for fracture benefit the most from hormone therapy, according to a first-of-its-kind study led by researchers at the University at Buffalo.

The study included nearly 10,000 participants from the Women's Health Initiative (WHI), a national, long-term study of more than 150,000 women.

"We found that women who are genetically at the highest fracture risk can enjoy the greatest protection from fracture when they use hormone therapy," said Heather Ochs-Balcom, associate professor of epidemiology and environmental health in UB's School of Public Health and Health Professions, who led the research team.

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