Osteomyelitis represents an infection of bone. In children, it occurs most commonly in the metaphysis of long bones. About two-thirds of cases occur in the lower extremity, with the femur and tibia most often affected. Osteomyelitis is subdivided based on chronicity into acute osteomyelitis (symptom duration less than two weeks), subacute osteomyelitis (symptom duration from two to six weeks), and chronic osteomyelitis (symptom duration longer than six weeks).
Osteomyelitis in children most commonly occurs due to hematogenous seeding, that is, circulating bacteria in the bloodstream land in the bone. Osteomyelitis can also occur as a result of local spread of bacteria from an adjacent infection or from direct inoculation due to an open fracture or puncture wound.
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