The objective of this 2-year study is to evaluate the safety, tolerability and disease modifying efficacy of SD 6010, an inhibitor of inducible nitric oxide synthase (iNOS), in overweight and obese subjects with knee osteoarthritis. The efficacy of SD-6010 will be evaluated by radiography using joint space narrowing in the medial tibiofemoral compartment of the study knee as the primary endpoint.
Read more: http://www.clinicaltrials.gov/ct2/show/NCT00565812?cond=%22Arthritis%22&lup_s=07/14/2011&lup_d=30
