Are male or female patients with osteoarthritis (OA), as determined by medical history and physical examination. Males and females with stable medical problems that, in the investigator's opinion, will not significantly alter the disposition of the drug, will not place the patient at increased risk by participating in the study, and will not interfere with interpretation of the data.

  1. Male patients: agree to use a reliable method of birth control during the study and for 3 months following the last dose of the investigational product
  2. Female patients: women not of child-bearing potential due to surgical sterilization (at least 6 weeks post surgical bilateral oophorectomy with or without hysterectomy or tubal ligation) confirmed by medical history, or menopause

Read more: http://www.clinicaltrials.gov/ct2/show/NCT01319929?cond=%22Arthritis%22&lup_s=07/28/2011&lup_d=30