While participating in physical activities such as bike riding, dancing, walking and gardening and mentally stimulating activities such as crosswords and reading may reduce the risk of Alzheimer's disease, they may not do so by affecting the underlying markers for the disease, according to a study published online in Neurology®, the medical journal of the American Academy of Neurology.

"While a lifelong history of physical and mental activity may support better memory and thinking performance, this relationship may possibly be separate from any protection against the markers of Alzheimer's disease in the brain," said study author Keith A.

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