Cartilage studies shed light on 'microdomains' and pave way to better treatment options.
Injury and degeneration of fibro-cartilaginous tissues, such as the knee meniscus and the intervertebral disc, have significant socioeconomic and quality-of-life costs. But the development of effective treatment strategies to address pathologies in these load-bearing tissues has been hindered by a lack of understanding of the relationships between their structure and their function.
Now, a team of researchers from the University of Delaware and the University of Pennsylvania has shed new light on this issue, laying the foundation for better treatment of injuries such as meniscus tears as well as new therapies for osteoarthritis and age-related degeneration.
