Scientists report first case of immunohistochemical marker confirming diagnosis of extra-axial dedifferentiated chordoma.
An exceptionally rare and aggressive malignant bone tumor was positively confirmed via the expressions of a DNA protein transcription factor, according to a recent study by American researchers.
"We herein report an exceptional case of extra-axial dedifferentiated chordoma confirmed by the expression of brachyury, the first case report of this kind," reported surgical pathologist Dr. Evita Bonita Henderson-Jackson and her research colleagues from Moffitt Cancer Center in Tampa, Florida, United States, in a case report offering literature review and pathologists' perspective, published by the open-access peer-reviewed journal Advances in Modern Oncology Research (AMOR).
