In my opinion, it will depend on the program. From what I can gather, many programs don't look at step 2 that closely, so many of the people that you will be competing with for interviews will have higher step 1 but no step 2 available. The purpose of a step 1 cutoff is so programs won't have to sort through the rest of your application to see if they want to offer you an interview. There are probably some programs out there that may give you the benefit of the doubt, but I'm willing to bet there are more that will screen you out. Just my opinion. You increase your odds by applying to as many programs as you can. Best of luck.