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Among postmenopausal women with osteoporosis at risk of fracture, daily injection of the drug abaloparatide for 18 months significantly reduced the risk of new vertebral and nonvertebral fractures compared with placebo, according to a study appearing in JAMA.

Osteoporosis is associated with substantial social, economic, and public health burdens. Based on 2010 U.S. Census data, a study estimated the prevalence of osteoporosis among women 50 to 69 years of age at 3.4 million. It has been estimated that the lifetime risk of osteoporotic fracture for a 60-year-old woman is 44 percent.

Researchers say a healthy lifestyle could lower levels of plaques and tangles that are a hallmark of Alzheimer's disease.

Published in the American Journal of Geriatric Psychiatry, the study found people with mild memory problems who followed a Mediterranean diet, engaged in regular physical activity, or who had a normal body mass index (BMI) were less likely to experience a buildup of beta-amyloid and tau proteins in the brain.

Sitting too much is detrimental to health, regardless of physical activity levels, say researchers.

In recent years, there has been an increasing number of studies documenting the harms of sedentary behavior - defined as any waking activity that involves sitting or lying down, such as watching TV or working on the computer.

Research has repeatedly linked sedentary behavior with increased risk of obesity, cardiovascular diseases, diabetes, and more.

Although gout has been studied for centuries, there are still many questions unanswered.

Gout is a rheumatic condition caused by a buildup of uric acid in the joints, known as hyperuricemia.

It is the most common form of inflammatory arthritis in men. Gout normally strikes in the base joint of the big toe and can be debilitatingly painful.

Researchers say switching from driving to cycling may benefit health.

The findings come from an international team of researchers - led by Dr. Audrey de Nazelle from the Centre for Environmental Policy at Imperial College London in the United Kingdom - who analyzed the data of around 11,000 adults across Europe.

The research forms a part of the Physical Activity through Sustainable Transport Approaches (PASTA) project, which aims to gain a better understanding of how different forms of transport influence the physical activity and overall health of the general public.

Researchers say aerobic physical activity could benefit the cognitive functioning of people with schizophrenia.

The researchers - including Joseph Firth of the Institute of Brain, Behavior and Mental Health at the University of Manchester in the United Kingdom - publish their findings in the journal Schizophrenia Bulletin.

Schizophrenia is a mental disorder estimated to affect around 1.1 percent of American adults.

Symptoms of the disorder include hallucinations, delusions, abnormal thought processes, and agitated body movements.

Here are five key notes:

1. Mako partial knee replacement is less invasive than traditional total knee surgery.

2. Mako advertises that, compared to total knee surgery, patients experience reduced pain, quicker recovery and minimal hospitalization following this partial knee replacement procedure.

3. Casa Colina is one of the first hospitals in its region to offer this surgery, which is performed with a surgeon-controlled robotic arm system.

4. This minimally invasive procedure is only offered to adults with early stage knee osteoarthritis, which has not yet reached three compartments of the knee.

Jonas R. Rudzki, MD, is an orthopedic surgeon at Washington Orthopaedics & Sports Medicine, a practice with offices in Washington, D.C., and Chevy Chase, Md. He specializes in sports medicine, with an emphasis on treating shoulder, knee and elbow injuries.

Researchers say that targeting senescent cells may have the potential to prevent or treat osteoarthritis.

Study co-author Dr. James Kirkland, director of the Robert and Arlene Kogod Center on Aging at Mayo Clinic in Rochester, MN, and colleagues publish their findings in The Journals of Gerontology, Series A: Biological Sciences and Medical Sciences.

Osteoarthritis (OA), also known as degenerative joint disease, is a condition in which cartilage - the tissue that protects the end of each bone in a joint - wears away, causing the underlying bones to rub together.